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Western blot analysis of extracts of various cell lines, using ZIC2 antibody (A15736) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 30s.
ZIC2 Rabbit pAb
Catalog No：AB-A15736
Manufacturer：ABclonal
Synonyms：ZIC2;HPE5
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ZIC2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ZIC2 (NP_009060.2). |
| Gene ID: | 7546 |
| Swiss prot: | O95409 |
| Molecular weight: | 55kDa |
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