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Western blot analysis of extracts of various cell lines, using XRCC1 antibody (A0442) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
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Immunohistochemistry of paraffin-embedded human colon carcinoma using XRCC1 Rabbit pAb (A0442) at dilution of 1:300 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse lung using XRCC1 Rabbit pAb (A0442) at dilution of 1:300 (40x lens).
XRCC1 Rabbit pAb
Catalog No：AB-A0442
Manufacturer：ABclonal
Synonyms：XRCC1;RCC
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | XRCC1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human XRCC1 (NP_006288.2). |
| Gene ID: | 7515 |
| Swiss prot: | P18887 |
| Molecular weight: | 69kDa |
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