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Western blot analysis of extracts of various cell lines, using XPC antibody (A8354) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 5s.
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Immunohistochemistry of paraffin-embedded human colon carcinoma using XPC Rabbit pAb (A8354) at dilution of 1:100 (40x lens).
XPC Rabbit pAb
Catalog No：AB-A8354
Manufacturer：ABclonal
Synonyms：XPC;RAD4;XP3;XPCC;p125
Applications：WB,IHC,IP
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | XPC Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-940 of human XPC (NP_004619.3). |
| Gene ID: | 7508 |
| Swiss prot: | Q01831 |
| Molecular weight: | 15kDa/101kDa/105kDa |
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