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Western blot analysis of extracts of various cell lines, using WWOX antibody (A12653) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
WWOX Rabbit pAb
Catalog No：AB-A12653
Manufacturer：ABclonal
Synonyms：WWOX;D16S432E;EIEE28;FOR;FRA16D;HHCMA56;PRO0128;SCAR12;SDR41C1;WOX1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | WWOX Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human WWOX (NP_057457.1). |
| Gene ID: | 51741 |
| Swiss prot: | Q9NZC7 |
| Molecular weight: | 4kDa/21kDa/23kDa/26kDa/35kDa/41kDa/46kDa |
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