Danicopan [Cas No. 1903768-17-1]
Catalog No：TA-T8509
Manufacturer：TargetMol
Synonyms：ACH-4471
CAS No.：1903768-17-1
Formula：C26H23BrFN7O3
MWt：580.41
€138,00 – €1.717,00
| Name: | Danicopan |
| Category: | Biochemicals |
| Description: | Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). |
| Pathway: | Immunology & Inflammation |
| Target: | Complement System |
| Receptor: | factor D |
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