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Western blot analysis of extracts of various cell lines, using VEGFR1 antibody (A1277) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded human placenta using FLT1 antibody (A1277) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat spleen using FLT1 antibody (A1277) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using FLT1 antibody (A1277) at dilution of 1:100 (40x lens).
VEGFR1 Rabbit pAb
Catalog No：AB-A1277
Manufacturer：ABclonal
Synonyms：FLT;FLT-1;VEGFR-1;VEGFR1;FLT1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | VEGFR1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human VEGFR1 (NP_001153392.1). |
| Gene ID: | 2321 |
| Swiss prot: | P17948 |
| Molecular weight: | 39kDa/41kDa/52- 82kDa/150kDa |
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