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Western blot analysis of extracts of various cell lines, using VDR antibody (A11743) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
VDR Rabbit pAb
Catalog No：AB-A11743
Manufacturer：ABclonal
Synonyms：VDR;NR1I1;PPP1R163
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | VDR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 128-427 of human VDR (NP_000367.1). |
| Gene ID: | 7421 |
| Swiss prot: | P11473 |
| Molecular weight: | 48kDa/53kDa |
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