Western blot analysis of extracts of various cell lines, using UVRAG antibody (A8462) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
UVRAG Rabbit pAb
Catalog No:AB-A8462
Manufacturer:ABclonal
Synonyms:UVRAG;DHTX;VPS38;p63
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | UVRAG Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2). |
Gene ID: | 7405 |
Swiss prot: | Q9P2Y5 |
Molecular weight: | 35kDa/78kDa |
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