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Western blot analysis of extracts of various cell lines, using UPK1A antibody (A12761) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 30s.
UPK1A Rabbit pAb
Catalog No：AB-A12761
Manufacturer：ABclonal
Synonyms：UPK1A;TSPAN21;UP1A;UPIA;UPKA
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | UPK1A Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-230 of human UPK1A (NP_008931.1). |
| Gene ID: | 11045 |
| Swiss prot: | O00322 |
| Molecular weight: | 28kDa/30kDa |
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