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Western blot analysis of extracts of various cell lines, using UNC13D antibody (A13141) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
UNC13D Rabbit pAb
Catalog No：AB-A13141
Manufacturer：ABclonal
Synonyms：UNC13D;FHL3;HLH3;HPLH3;Munc13-4
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | UNC13D Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 891-1090 of human UNC13D (NP_954712.1). |
| Gene ID: | 201294 |
| Swiss prot: | Q70J99 |
| Molecular weight: | 41kDa/123kDa/128kDa |
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