Tuxobertinib [Cas No. 2414572-47-5]
Catalog No：TA-T9072
Manufacturer：TargetMol
CAS No.：2414572-47-5
Formula：C29H29ClN6O4
MWt：561.03
€51,00 – €1.145,00
| Name: | BDTX-189 |
| Category: | Biochemicals |
| Description: | BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity. |
| Pathway: | Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Apoptosis |
| Target: | BTK,EGFR,HER,TNF |
| Receptor: | BLK,EGFR,HER2,RIPK2 |
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