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Western blot analysis of extracts of various cell lines, using UMOD Antibody (A1920) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).
UMOD Rabbit pAb
Catalog No：AB-A1920
Manufacturer：ABclonal
Synonyms：UMOD;ADMCKD2;FJHN;HNFJ;HNFJ1;MCKD2;THGP;THP
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | UMOD Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 315-615 of human UMOD (NP_001008390.1). |
| Gene ID: | 7369 |
| Swiss prot: | P07911 |
| Molecular weight: | 55kDa/66kDa/67kDa/69kDa/73kDa |
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