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Western blot analysis of extracts of various cell lines, using UGT1A6 Rabbit pAb (A17166) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
UGT1A6 Rabbit pAb
Catalog No：AB-A17166
Manufacturer：ABclonal
Synonyms：UGT1A6;GNT1;HLUGP;HLUGP1;UDPGT;UDPGT 1-6;UGT1;UGT1A6S;UGT1F;UDPGT1-6
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | UGT1A6 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2). |
| Gene ID: | 54578 |
| Swiss prot: | P19224 |
| Molecular weight: | 29kDa/50kDa/60kDa |
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