Western blot analysis of extracts of rat skin, using TYR antibody (A13608) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
TYR Rabbit pAb
Catalog No:AB-A13608
Manufacturer:ABclonal
Synonyms:TYR;ATN;CMM8;OCA1;OCA1A;OCAIA;SHEP3
Applications:WB,IF
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TYR Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3′ half of this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-340 of human TYR (NP_000363.1). |
Gene ID: | 7299 |
Swiss prot: | P14679 |
Molecular weight: | 42kDa/60kDa |
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