Western blot analysis of extracts of HeLa cells, using TTK antibody (A2500) at 1:2000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
TTK Rabbit pAb
Catalog No:AB-A2500
Manufacturer:ABclonal
Synonyms:TTK;CT96;ESK;MPH1;MPS1;MPS1L1;PYT
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TTK Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 517-856 of human TTK (NP_001160163.1). |
Gene ID: | 7272 |
Swiss prot: | P33981 |
Molecular weight: | 96kDa/97kDa |
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