Western blot analysis of extracts of various cell lines, using TSN Rabbit pAb (A18590) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
TSN Rabbit pAb
Catalog No:AB-A18590
Manufacturer:ABclonal
Synonyms:BCLF-1;C3PO;RCHF1;REHF-1;TBRBP;TRSLN;TSN;translin
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TSN Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1). |
Gene ID: | 7247 |
Swiss prot: | Q15631 |
Molecular weight: | 17kDa/26kDa |
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