TSLP Rabbit pAb
Catalog No:AB-A1881
Manufacturer:ABclonal
Synonyms:TSLP
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | TSLP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human TSLP (NP_149024.1). |
Gene ID: | 85480 |
Swiss prot: | Q969D9 |
Molecular weight: | 7kDa/18kDa |
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