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Western blot analysis of extracts of various cell lines, using Tropomyosin 1 Rabbit mAb (A8723) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3s.
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Immunohistochemistry of paraffin-embedded rat heart using Tropomyosin 1 Rabbit mAb (A8723) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using Tropomyosin 1 Rabbit mAb (A8723) at dilution of 1:100 (40x lens).
Tropomyosin 1 Rabbit mAb
Catalog No：AB-A8723
Manufacturer：ABclonal
Synonyms：C15orf13, CMD1Y, CMH3, HEL-S-265, HTM-alpha, LVNC9, TMSA
Applications：WB,IHC,IF,IP
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | Tropomyosin 1 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human Tropomyosin 1 |
| Gene ID: | 7168 |
| Swiss prot: | P09493 |
| Molecular weight: | 33kDa |
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