Western blot analysis of extracts of various cell lines, using TrkA antibody (A2098) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
TrkA Rabbit pAb
Catalog No:AB-A2098
Manufacturer:ABclonal
Synonyms:NTRK1;MTC;TRK;TRK1;TRKA;Trk-A;p140-TrkA
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TrkA Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TrkA (NP_002520.2). |
Gene ID: | 4914 |
Swiss prot: | P04629 |
Molecular weight: | 77kDa/83kDa/86kDa/87kDa |
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