TRAP-14
Catalog No：CP-PARP-022A
Manufacturer：CPC Scientific
Size：1 mg
CAS No.：137339-65-2
Formula：C81H118 N20O23
MWt：1,740
€72,00
| Product Name: | TRAP-14 |
| Category: | Peptides |
| Three letter sequence: | H-Ser-Phe- Leu-Leu-Arg- Asn-Pro-Asn- Asp-Lys-Tyr- Glu-Pro-Phe- OH Trifluoroacet ate salt |
| One letter sequence: | SFLLRNPNDKY EPF |
| Description: | This peptide is a 14- amino acid peptide mimicking the potent thrombin receptor activator as well as an effective agonist for platelet activation. This peptide is the fragment 42-55 of the human thrombin receptor and fully reproduces the action of thrombin on MMPs in vascular endothelial cells. This peptide (TRP- 14) may signal a variety of thrombin鈥檚 responses and has been shown to cause platelet aggregation that can evoke a wide range of G- protein dependent responses. |
| Literature References: | T.-K.H.Vu et al., Cell, 64, 1057 (1991) Y.Maruyama et al., Biochem. Biophys. Res. Commun., 199, 1262 (1994) Duhamel-Cl茅rin, E. et al. Arterioscler. Thromb. Vasc. Biol. 17, 1931 (1997); Vassallo, R. et al. J. Biol. Chem. 267, 6081 (1992); Y. Sugama and AB. Malik. Circ. Res. 71, 1015 (1992). |
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