Quisinostat dihydrochloride [Cas No. 875320-31-3]
Catalog No：TA-T6865
Manufacturer：TargetMol
Synonyms：Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl
CAS No.：875320-31-3
Formula：C21H28Cl2N6O2
MWt：467.39
€59,00 – €947,00
| Name: | Quisinostat 2HCl |
| Category: | Biochemicals |
| Description: | Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2. |
| Pathway: | Chromatin/Epigenetic, DNA Damage/DNA Repair, NF-Κb |
| Target: | HDAC inhibitor |
| Receptor: | HDAC1, HDAC10, HDAC11, HDAC2, HDAC4 |
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