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Western blot analysis of extracts of various cell lines, using TNFSF12 antibody (A5659) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat brain using TNFSF12 Antibody (A5659) at dilution of 1:100 (20x lens).
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Immunohistochemistry of paraffin-embedded human tonsil using TNFSF12 Antibody (A5659) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using TNFSF12 Antibody (A5659) at dilution of 1:100 (40x lens).
TNFSF12 Rabbit pAb
Catalog No：AB-A5659
Manufacturer：ABclonal
Synonyms：TNFSF12;APO3L;DR3LG;TNLG4A;TWEAK
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TNFSF12 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-123 of human TNFSF12 (NP_003800.1). |
| Gene ID: | 8742 |
| Swiss prot: | O43508 |
| Molecular weight: | 27kDa/36kDa |
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