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Western blot analysis of extracts of various cell lines, using TNFRSF13C antibody (A14299) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 20s.
TNFRSF13C Rabbit pAb
Catalog No：AB-A14299
Manufacturer：ABclonal
Synonyms：TNFRSF13C;BAFF-R;BAFFR;BROMIX;CD268;CVID4;prolixin
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TNFRSF13C Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human TNFRSF13C (NP_443177.1). |
| Gene ID: | 115650 |
| Swiss prot: | Q96RJ3 |
| Molecular weight: | 18kDa |
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