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Western blot analysis of extracts of various cell lines, using TNFR1/TNFRSF1A antibody (A1540) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat lung using TNFR1/TNFRSF1A Rabbit pAb (A1540) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat spleen using TNFR1/TNFRSF1A Rabbit pAb (A1540) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using TNFR1/TNFRSF1A Rabbit pAb (A1540) at dilution of 1:100 (40x lens).
TNFR1/TNFRSF1A Rabbit pAb
Catalog No：AB-A1540
Manufacturer：ABclonal
Synonyms：TNFRSF1A;CD120a;FPF;TBP1;TNF-R;TNF-R-I;TNF-R55;TNFAR;TNFR1;TNFR55;TNFR60;p55;p55-R;p60
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TNFR1/TNFRSF1A Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-211 of human TNFR1/TNFRSF1A (NP_001056.1). |
| Gene ID: | 7132 |
| Swiss prot: | P19438 |
| Molecular weight: | 24kDa/25kDa/38kDa/50kDa |
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