Western blot analysis of extracts of various cell lines, using TLR5 Rabbit mAb (A8765) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
TLR5 Rabbit mAb
Catalog No:AB-A8765
Manufacturer:ABclonal
Synonyms:MELIOS, SLE1, SLEB1, TIL3
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | TLR5 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009] |
Immunogen: | A synthesized peptide derived from human TLR5 |
Gene ID: | 7100 |
Swiss prot: | O60602 |
Molecular weight: | 97kDa |
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