Western blot analysis of extracts of various cell lines, using Thioredoxin reductase 1 (Thioredoxin reductase 1 (TXNRD1 ) ) antibody (A16631) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Thioredoxin reductase 1 (TXNRD1 ) Rabbit pAb
Catalog No:AB-A16631
Manufacturer:ABclonal
Synonyms:TXNRD1;GRIM-12;TR;TR1;TRXR1;TXNR
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Thioredoxin reductase 1 (TXNRD1 ) Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. |
Immunogen: | Recombinant protein of human Thioredoxin reductase 1 (Thioredoxin reductase 1 (TXNRD1 ) ) |
Gene ID: | 7296 |
Swiss prot: | Q16881 |
Molecular weight: | 50kDa/54kDa/59kDa/60kDa/65kDa/67kDa/70kDa |
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