Indoximod [Cas No. 110117-83-4]
Catalog No：TA-T6543
Manufacturer：TargetMol
Synonyms：1-Methyl-D-tryptophan,NLG-8189,Indoximod (NLG-8189）
CAS No.：110117-83-4
Formula：C12H14N2O2
MWt：218.25
€50,00
| Name: | Indoximod |
| Category: | Biochemicals |
| Description: | Indoximod is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy. |
| Pathway: | Metabolism |
| Target: | IDO inhibitor |
| Receptor: | IDO |
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