Western blot analysis of extracts of various cell lines, using TGFB1 antibody (A2124) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
TGFB1 Rabbit pAb
Catalog No:AB-A2124
Manufacturer:ABclonal
Synonyms:TGFB1;CED;DPD1;LAP;TGFB;TGFbeta;TGF-β
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TGFB1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-280 of human TGFB1 (NP_000651.3). |
Gene ID: | 7040 |
Swiss prot: | P01137 |
Molecular weight: | 44kDa |
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