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Western blot analysis of extracts of various cell lines, using TGFBR2 antibody (A1415) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded human appendix using TGF beta Receptor II (TGF beta Receptor II (TGFBR2)) antibody (A1415) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human breast cancer using TGF beta Receptor II (TGF beta Receptor II (TGFBR2)) antibody (A1415) at dilution of 1:100 (40x lens).
TGF beta Receptor II (TGFBR2) Rabbit pAb
Catalog No：AB-A1415
Manufacturer：ABclonal
Synonyms：AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;TGFR-2;TGFbeta-RII;TGF beta Receptor II;TGFBR2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TGF beta Receptor II (TGFBR2) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-280 of human TGF beta Receptor II (TGF beta Receptor II (TGFBR2)) (NP_003233.4). |
| Gene ID: | 7048 |
| Swiss prot: | P37173 |
| Molecular weight: | 64kDa/67kDa |
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