SGC2085 HCl [Cas No. 1821908-49-9]
Catalog No：TA-T4013
Manufacturer：TargetMol
CAS No.：1821908-49-9
Formula：C19H24N2O2﹞HCl
MWt：348.87
€95,00 – €2.064,00
| Name: | SGC2085 HCl |
| Category: | Biochemicals |
| Description: | SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo. |
| Pathway: | Chromatin/Epigenetic |
| Target: | Histone Methyltransferase inhibitor |
| Receptor: | Coactivator Associated Arginine Methyltransferase 1 (CARM1) |
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