Western blot analysis of extracts of various cell lines, using TBL1X antibody (A15102) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
TBL1X Rabbit pAb
Catalog No:AB-A15102
Manufacturer:ABclonal
Synonyms:TBL1X;EBI;SMAP55;TBL1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TBL1X Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TBL1X (NP_005638.1). |
Gene ID: | 6907 |
Swiss prot: | O60907 |
Molecular weight: | 57kDa/62kDa |
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