Tau Peptide (244-274) (Repeat 1 domain)
Catalog No:CP-TAUP-003
Manufacturer:CPC Scientific
Size:1 mg
MWt:3,300
€77,00
Product Name: | Tau Peptide (244-274) (Repeat 1 domain) |
Category: | Peptides |
Three letter sequence: | Ac-Gln-Thr- Ala-Pro-Val- Pro-Met-Pro- Asp-Leu-Lys- Asn-Val-Lys- Ser-Lys-Ile- Gly-Ser-Thr- Glu-Asn-Leu- Lys-His-Gln- Pro-Gly-Gly- Gly-Lys |
One letter sequence: | Ac- QTAPVPMPDLK NVKSKIGSTEN LKHQPGGGK |
Description: | TAU proteins belong to the microtubule- associated protein (MAP) family and are involved in the pathogenesis of Alzheimer鈥檚 disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1- R4), in addition to the presence or absence of one or two insert domains at the amino-terminus (see figure below). Tau Peptide (244- 274) is a 31-amino |
Literature References: | Buee, L. et al. Brain Res Rev 33 95 (2000); Trinczek, B. et al. Mol Biol Cell 6, 1887 (1995). |
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