Poziotinib hydrochloride [Cas No. 1429757-68-5]
Catalog No：TA-T8758
Manufacturer：TargetMol
Synonyms：NOV120101 hydrochloride,HM 781-36B hydrochloride
CAS No.：1429757-68-5
Formula：C23H22Cl3FN4O3
MWt：527.8
€50,00 – €713,00
| Name: | Poziotinib hydrochloride |
| Category: | Biochemicals |
| Description: | Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity. |
| Pathway: | Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors |
| Target: | EGFR |
| Receptor: | EGFR |
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