Mollugin [Cas No. 55481-88-4]
Catalog No:TA-T3673
Manufacturer:TargetMol
Synonyms:Rubimaillin
CAS No.:55481-88-4
Formula:C17H16O4
MWt:284.3
€16,00 – €297,00
Name: | Mollugin |
Category: | Biochemicals |
Description: | Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression. |
Pathway: | Angiogenesis, Chromatin/Epigenetic, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells |
Target: | HER inhibitor, JAK inhibitor |
Receptor: | HER2, JAK2 |
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