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Western blot analysis of extracts of various cell lines, using SURF1 antibody (A12521) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3s.
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Immunohistochemistry of paraffin-embedded rat kidney using SURF1 antibody (A12521) at dilution of 1:100 (40x lens).
SURF1 Rabbit pAb
Catalog No：AB-A12521
Manufacturer：ABclonal
Synonyms：SURF1;CMT4K
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SURF1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-275 of human SURF1 (NP_003163.1). |
| Gene ID: | 6834 |
| Swiss prot: | Q15526 |
| Molecular weight: | 31kDa/33kDa |
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