Sulindac [Cas No. 38194-50-2]
Catalog No：TA-T0459
Manufacturer：TargetMol
Synonyms：MK-231,Clinoril,Arthrocine,Sulindac sulfoxide
CAS No.：38194-50-2
Formula：C20H17FO3S
MWt：356.41
€30,00 – €97,00
| Name: | Sulindac |
| Category: | Biochemicals |
| Description: | Sulindac is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway, this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death. |
| Pathway: | Immunology & Inflammation, Neuroscience |
| Target: | COX inhibitor |
| Receptor: | COX |
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