Western blot analysis of extracts of various cell lines, using STX1A antibody (A5570) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
STX1A Rabbit pAb
Catalog No:AB-A5570
Manufacturer:ABclonal
Synonyms:STX1A;HPC-1;P35-1;STX1;SYN1A;syntaxin-1A
Applications:WB,IHC,IF
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | STX1A Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human STX1A (NP_004594.1). |
Gene ID: | 6804 |
Swiss prot: | Q16623 |
Molecular weight: | 28kDa/29kDa/33kDa |
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