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Western blot analysis of extracts of various cell lines, using STK36 antibody (A10974) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
STK36 Rabbit pAb
Catalog No：AB-A10974
Manufacturer：ABclonal
Synonyms：STK36;FU
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€125,00 – €370,00
| Product Name: | STK36 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human STK36 (NP_056505.2). |
| Gene ID: | 27148 |
| Swiss prot: | Q9NRP7 |
| Molecular weight: | 141kDa/143kDa |
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