Western blot analysis of extracts of various cell lines, using STAT6 antibody (A19120) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
STAT6 Rabbit mAb
Catalog No:AB-A19120
Manufacturer:ABclonal
Synonyms:D12S1644;IL-4-STAT;STAT6B;STAT6C;STAT6
Applications:WB,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | STAT6 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
Immunogen: | A synthesized peptide derived from human STAT6 |
Gene ID: | 6778 |
Swiss prot: | P42226 |
Molecular weight: | 94kDa |
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