X-376 [Cas No. 1365267-27-1]
Catalog No:TA-T3550
Manufacturer:TargetMol
Synonyms:X-376,X-396
CAS No.:1365267-27-1
Formula:C25H25Cl2FN5O3
MWt:547.41
€38,00 – €678,00
Name: | Ensartinib |
Category: | Biochemicals |
Description: | Ensartinib (X-396) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. |
Pathway: | Angiogenesis,Tyrosine Kinase/Adaptors |
Target: | ALK inhibitor,c-Met/HGFR |
Receptor: | ALK,MET |
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