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Western blot analysis of extracts of various cell lines, using SREBP1 antibody (A15586) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
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Immunohistochemistry of paraffin-embedded Human liver cancer using SREBP1 antibody (A15586) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Mouse liver using SREBP1 antibody (A15586) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Rat liver using SREBP1 antibody (A15586) at dilution of 1:100 (40x lens).
SREBP1 Rabbit pAb
Catalog No：AB-A15586
Manufacturer：ABclonal
Synonyms：SREBF1;SREBP-1c;SREBP1;SREBP1a;bHLHd1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SREBP1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SREBF1 (NP_001005291.1). |
| Gene ID: | 6720 |
| Swiss prot: | P36956 |
| Molecular weight: | 45kDa/48kDa/111kDa/113kDa/121kDa/124kDa |
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