Western blot analysis of extracts of 293T cells, using SQSTM1/p62 Rabbit pAb (A11246) at 1:1000 dilution.293T cells were treated by Chloroquine (50 μM) at 37℃ for 20 hours.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
SQSTM1/p62 Rabbit pAb
Catalog No:AB-A11246
Manufacturer:ABclonal
Synonyms:SQSTM1;A170;DMRV;FTDALS3;NADGP;OSIL;PDB3;ZIP3;p60;p62;p62B
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SQSTM1/p62 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human SQSTM1/p62 (NP_003891.1). |
Gene ID: | 8878 |
Swiss prot: | Q13501 |
Molecular weight: | 38kDa/47kDa |
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