Western blot analysis of extracts of PC-3 cells, using SPOP Rabbit mAb (A19578) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
SPOP Rabbit mAb
Catalog No:AB-A19578
Manufacturer:ABclonal
Synonyms:BTBD32, TEF2
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | SPOP Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human SPOP |
Gene ID: | 8405 |
Swiss prot: | O43791 |
Molecular weight: | 42kDa |
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