SPHK1 Rabbit pAb
Catalog No:AB-A0139
Manufacturer:ABclonal
Synonyms:SPHK1;SPHK
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SPHK1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-384 of human SPHK1 (NP_001136074.1). |
Gene ID: | 8877 |
Swiss prot: | Q9NYA1 |
Molecular weight: | 42kDa/43kDa/51kDa |
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