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Western blot analysis of extracts of various cell lines, using SPAG6 antibody (A3088).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
SPAG6 Rabbit pAb
Catalog No：AB-A3088
Manufacturer：ABclonal
Synonyms：SPAG6;CT141;Repro-SA-1;pf16
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SPAG6 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human SPAG6 (NP_758442.1). |
| Gene ID: | 9576 |
| Swiss prot: | O75602 |
| Molecular weight: | 30kDa/49kDa/52kDa/55kDa/63kDa |
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