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Western blot analysis of extracts of various cell lines, using SORD antibody (A15727) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
SORD Rabbit pAb
Catalog No：AB-A15727
Manufacturer：ABclonal
Synonyms：SORD;HEL-S-95n;SORD1
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SORD Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-357 of human SORD (NP_003095.2). |
| Gene ID: | 6652 |
| Swiss prot: | Q00796 |
| Molecular weight: | 10kDa/38kDa |
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