Western blot analysis of extracts of various cell lines, using SNRPN antibody (A15726) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
SNRPN Rabbit pAb
Catalog No:AB-A15726
Manufacturer:ABclonal
Synonyms:SNRPN;HCERN3;PWCR;RT-LI;SM-D;SMN;SNRNP-N;SNURF-SNRPN;sm-N;PWS
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SNRPN Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5′ untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5′ UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPN (NP_003088.1). |
Gene ID: | 6638 |
Swiss prot: | P63162 |
Molecular weight: | 24kDa/25kDa |
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