Western blot analysis of extracts of various cell lines, using SNRNP200 antibody (A6063) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
SNRNP200 Rabbit pAb
Catalog No:AB-A6063
Manufacturer:ABclonal
Synonyms:SNRNP200;ASCC3L1;BRR2;HELIC2;RP33;U5-200KD;SNRNP200
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SNRNP200 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2). |
Gene ID: | 23020 |
Swiss prot: | O75643 |
Molecular weight: | 71kDa/244kDa |
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