SmMLCKp, Smooth- Muscle Myosin Light-Chain Kinase (796- 815), Calmodulin Binding
Catalog No:CP-SIGN-013
Manufacturer:CPC Scientific
Size:1 mg
MWt:2,279
€129,00
Product Name: | SmMLCKp, Smooth- Muscle Myosin Light-Chain Kinase (796- 815), Calmodulin Binding |
Category: | Peptides |
Three letter sequence: | Ala-Arg-Arg- Lys-Trp-Gln- Lys-Thr-Gly- His-Ala-Val- Arg-Ala-Ile- Gly-Arg-Leu- Ser-Ser |
One letter sequence: | ARRKWQKTGH AVRAIGRLSS |
Description: | This is amino acids 796 to 815 fragment of the chicken gizzard smooth- muscle myosin light- chain kinase (smMLCKp or P7) peptide, calmodulin (CaM)-binding domain . It retains its affinity for CaM and represents an adequate model for a complex of CaM with intact smMLCK protein. In the globular (Ca2+)4- CaM-P7 complex, the protein is wrapped around the – helical peptide. All the lysine and arginine charges of P7 are in close contact with the negatively charged side chains of the |
Literature References: | Frederick, K. et al. Nature 448, 325 (2007); Andr茅. I. et al. Biophys. J. 90, 2903 (2006) |
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