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Western blot analysis of extracts of various cell lines, using SLC7A11/xCT antibody (A13685) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
SLC7A11/xCT Rabbit pAb
Catalog No：AB-A13685
Manufacturer：ABclonal
Synonyms：SLC7A11;CCBR1;xCT
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SLC7A11/xCT Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A11/xCT (NP_055146.1). |
| Gene ID: | 23657 |
| Swiss prot: | Q9UPY5 |
| Molecular weight: | 55kDa |
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